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Probenecid is a representative drug used in the treatment of gout.
In the present study, we investigated whether probenecid can affect osteoclast formation through the inhibition of reactive oxygen species (ROS) formation in RAW264. In Parkinson's disease (PD) research, human neuroblastoma and immortalized neural cell lines have been widely used as models.
Here we show that inactivation of the non-homologous end-joining (NHEJ) activity of DNA-PKcs prevented DNA damage-induced expansion of FA pre-leukemic hematopoietic stem cells (HSCs).
We investigated the effect of administration of MSC-MVs on the therapeutic potential of carbon tetrachloride (CCL) induced liver fibrosis in rats.
Isr Med Assoc J 2019 Aug;21(8):546-551Department of Family Medicine and Siaal Research Center for Family Practice and Primary Care, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.: The Bedouins living in southern Israel are a Muslim-Arab population that is transitioning from a nomadic lifestyle to life in permanent settlements.
This study aims at investigating the effect of AD-MSCs conditioned medium (CM) on human sperm parameters in the presence and absence of HO-induced OS. PSMD10, a proteasome assembly chaperone, is a widely known oncoprotein which aspects many hall mark properties of cancer.
However, except proteasome assembly chaperon function its role in normal cell function remains unknown. Department of Biological Science and Technology, National Pingtung University of Science and Technology, Neipu, Taiwan.However, in most cases, cancer cells seem to be resistant to cellular reprogramming.